The entire last round could not be played as originally scheduled over the weekend due to virus reasons and scheduling conflicts, but one game from it was played on Wednesday ahead of this round. Pamela-Therese Effangova led Hradec Kralove past Petra Malikova and KP Brno. Two games from this round were played, starting on Saturday with Brionna Jones leading USK Praha past Hradec Kralove 95-65. On Sunday, it was an easy 85-49 win for Ludmila Dudackova and KP Brno over Trutnov.
January 19, 2022
KP Brno vs. Hradec Kralove 77-81 KPB Malikova 21/6r Dudackova 19 Akl 12 Stejskalova 12 Kucowski 10/11r Fadrhonsova 3 HKR Effangova 25 Sotolova 16 Fiserova 15/11r
January 22, 2022
Hradec Kralove vs. USK Praha 65-95 HKR Cuperkova 16 Dautovic 13/6r USK Jones 31/7r Stankovic 12/6r Oblak 10 Conde 8 Thomas 6 Vorackova 4
January 23, 2022
KP Brno vs. Lokomotiva Trutnov 85-49 KPB Dudackova 21/12r Akl 16 Malikova 13 Stejskalova 12 Kucowski 6/12r Fadrhonsova 6 TRU Kralova 16/7r