May 20, 2022
Both series continued on Friday with teams looking for sweeps or extending their seasons. Johanne Gomis knew that a loss would put her announced retirement into effect immediately and she and Villeneuve looked ready to force a deciding game early. Aleksandra Crvendakic paced Lyon again and they fought back at home for the 83-76 win to advance. Landes also started well in their bid to avoid elimination, but Bourges took the lead only for Marine Fauthoux to fire the hosts back in front for a 71-70 win and to set up one game on Monday.
Lyon vs. Villeneuve 83-76 LYO Crvendakic 24 Alexander 14/11r Johannes 13 Burdick 12 Chevaugeon 12 Allemand 7/7a Jocyte 0 VIL Gomis 21 Diallo 16/7r Diaby 10 Anderson 6
Lyon wins series 2-0
Landes vs. Bourges 71-70 LAN Fauthoux 26 Magarity 14 Vukosavljevic 5 Dumerc 2 Tolo 2 Harmon 0 BRG Eldebrink 18 Rupert 15/6r Guapo 11/6r Yacoubou 10 Mann 2 Miyem 2
Series tied 1-1