The last game from Round 16 was played on Wednesday with Shae Kelley nearly helping San Martino di Lupari pulling off an upset, but Venezia left with a 72-67 win. Round 19 was then completed on Thursday with Laura Spreafico pacing Costa Masnaga in a 72-57 win over Moncalieri. A couple of games had to move to accommodate continental play, but this round did start with a 76-70 Faenza win over Empoli on Saturday. On Sunday, Maggie Lucas tried to lead Sassari again, but it was not enough and they lost to Moncalieri 70-68. Ragusa was too shorthanded to put up much of a fight against Bologna, losing 84-57. San Martino di Lupari won 76-54 over Broni in the only game scheduled at the traditional time. The day ended with a 63-48 Lucca win over Sesto San Giovanni.
February 16, 2022
San Martino di Lupari vs. Venezia 67-72 SAM Kelley 24/7r Milazzo 12 Mitchell 9 VEN Carangelo 15 Ndour-Fall 14 Bestagno 12/9r Anderson 10 Thornton 9 Attura 5 Penna 0
February 17, 2022
Costa Masnaga vs. Moncalieri 72-57 COS Spreafico 26 M. Villa 17/6r Vaughn 16/16r Jablonowski 5/7r MON Miletic 16 Toffolo 10/6r
February 19, 2022
Faenza vs. Empoli 76-70 FAE Kunaiyi-Akpanah 17/17r Davis 17 Morsiani 13/7r Kantzy 6 EMP Rembiszewska 18/6r Stoichkova 14 Jeune 12 Williams 8/11r
February 20, 2022
Moncalieri vs. Sassari 70-68 MON Miletic 19/14r Cordola 14 SAS Lucas 24 Moroni 12/6r Dell’Olio 12 Skoric 11/8r
Ragusa vs. Bologna 57-84 RAG Tagliamento 19/6r Kuier 12/8r Santucci 11/7r Romeo 11 BOL Zandalasini 15 Turner 12/7r Cinili 11 Pasa 11 Barberis 10 Hines-Allen 6/6r
Broni vs. San Martino di Lupari 54-76 BRO Galbiati 14 Smith 13/6r Dedic 11/6r SAM Kelley 19/9r Milazzo 18 Mitchell 12 Pastrello 10/10r
Lucca vs. Sesto San Giovanni 63-48 LUC Miccoli 13 Dietrick 10/7a Wiese 9/17r Gianolla 2 SES Dotto 11 Gwathmey 11 Raca 10/7r Graves 4