The quarterfinals were played over the weekend, starting with a fun game on Friday that saw Villeneuve come back late to win 69-68 over Tarbes. On Saturday, it was Landerneau rolling past Hainaut 88-56. On Sunday, Lattes Montpellier was severely shorthanded and had to rely nearly exclusively on their starters, but they did not give up after a halftime deficit and Elodie Naigre helped them fight back and force overtime, but Bourges did enough in the extra period to win 80-75. Landes defeated Lyon 72-60 in the last game of the weekend.
January 21, 2022
Tarbes vs. Villeneuve 68-69 TAR Brezinova 17 Pardon 16/11a Wojta 13/11r Samson 10 Ewodo 10 VIL Anderson 15 Salaun 12 Ygueravide 11 Diallo 10
January 22, 2022
Landerneau vs. Hainaut 88-56 BRE Amukamara 18 Slocum 13 Gaillou-Loko 13 Geiselsoder 9/6r Ibekwe 8 HAI Evrard 14 Okou-Zouzouo 13 Williams 8/6r Ewodo 4
January 23, 2022
Bourges vs. Lattes Montpellier 80-75(OT) BRG Miyem 17 Hampton 17 Rupert 14/17r Mann 14/6r Yacoubou 6 MTP Naigre 23/6r Epoupa 15 Peters 14/8r Toure 12/6r
Landes vs. Lyon 72-60 LAN Magarity 18/12r Turcinovic 13 Chery 10/6r Tolo 9/7r Fauthoux 8 Harmon 5/7r LYO Crvendakic 14 Chartereau 11 Johannes 9/6a Burdick 8/6r Jocyte 3