The last game from Round 2 was played on the Wednesday before this round and Nesibe rolled past Elazig 96-58. This round was played on Saturday, starting with an easy 72-45 Galatasaray win over Antalya. Nesibe won 79-61 at Botas. Besiktas was able to make a couple of signings over the break and least fill the foreign player spots, but Meighan Simmons and company still fell to Elazig, which was paced by Kolby Morgan and Lindsey Pulliam. Alexis Prince and Elina Babkina fired Cankaya University past Aaryn Ellenberg-Wiley and Hatay 101-87. Orman had a strong second half win a 97-70 win over Bursa. Izmit did enough late to escape Destiny Slocum and Kayseri 68-64. It was the first big test for whether Cukurova will be a title contender and they kept it respectable behind Tiffany Hayes, but did lose 72-59 to Fenerbahce.
November 17, 2021
Nesibe vs. Elazig 96-58 NES Coates 19/8r Nacickaite 17 Snytsina 13/6r Thomas 13/7a ELA Pulliam 17 Morgan 17 Dabakoglu 12 Yalcinkaya 0
November 20, 2021
Galatasaray vs. Antalya 72-45 GAL Krajisnik 13/7r Basaran 12 Gulcan 11/7r Williams 9 K. Davis 6 Steinberga 4/8r ANT G. Davis 14/8r Jones 9 Ozelci 3
Botas vs. Nesibe 61-79 BOT Davis 16 Jurjane 10/10r Cora 10 NES Thomas 19/7r Snytsina 18 Eldas 10/6r Coates 9/15r Nacickaite 9
Elazig vs. Besiktas 83-77 ELA Morgan 27/8r Pulliam 24 Razheva 18 Yalcinkaya 2/6r BES Simmons 26 Johnson 15/12r Jakobsone 13 McCall 6 Kepenc 3
Cankaya Universitesi vs. Hatay 101-87 CAU Prince 27/10r Babkina 27/7a White 18/6r/9a Yaya 16/6r/11a Murat 10 HAT Ellenberg-Wiley 25/7r/6a Brown 19/8r Caglar 10/10r/7a
Bursa vs. Orman 70-97 BUR Macaulay 18/6r Cuic 17 Doyle 14 ORM McCowan 18/10r Robinson 16 Lucet 15/9r Uzun 13/6a Fitik 11 Gezgin 11
Kayseri vs. Izmit 64-68 KAY Slocum 21/10r Sventoraite 14/11r Williams 11/10r IZM Fields 18 Korkmaz 14 Higgins 10/11r Turk 8/6r
Fenerbahce vs. Cukurova 72-59 FEN Iagupova 15/6a McBride 15 Williams 12/11r Canitez 12 Cakir 8 Zahui B 4 Stokes 0/6r CUK Hayes 24/6r Zellous 15/8r Fagbenle 8 Hollingsworth 4 Anigwe 2