Group A:
October 20, 2021
USK Praha vs. Szekszard 83-56 USK Jones 18/7r Thomas 14/10r Conde 12 Oblak 12/7a Stankovic 8/9r Vorackova 3 KSC Friskovec 15 Milic 14 Goree 8 Vorpahl 6 Krnjic 4
Reyer Venezia vs. Avenida 56-71 REYER Thornton 14 Anderson 14/8a Bestagno 10 Attura 4 Penna 0 AVEN Kat. Samuelson 16 Fasoula 14 Hof 12/9r Kar. Samuelson 7 Vilaro 6 Rodriguez 5 Evans 3 Alarie 2 Cazorla 2
Lattes Montpellier vs. Ekaterinburg 73-92 BLMA Toure 18 Wallace 16 Peters 12 Epoupa 12 Warley-Talbert 0 UMMC Bentley 20/8a Jones 19/9r Vadeeva 17/8r Shilova 15 Meesseman 12/6r/8a Torrens 6/8r Belyakova 3
October 21, 2021
Riga vs. MBA Moscow 64-59 TTT Thomas 19 Pulvere 16 Sarauskaite 12/8r Handy 6 Basko 5/6r MBA Maiga 13/9r Logunova 11/6r Korshakova 11
Group B:
October 20, 2021
Galatasaray vs. Arka Gdynia 71-60 GALA Williams 16 Krajisnik 15/7r Steinberga 13 Dungee 4 VBW Gustafson 26/10r Kunek 16/10r/6a Bertsch 7/6r Kastanek 2
Landes vs. Dynamo Kursk 78-75 BLAN Dumerc 16 Tolo 14/10r Fauthoux 14 Chery 12/8r Paget 11 Ajemba /10r DK Lisec 18/9r Ogunbowale 17 Howard 14/6r Prince 7 Baric 7
Girona vs. Fenerbahce 71-59 GIRO Burke 28/7r Gardner 12/10r Reisingerova 7/6r Flores 4 Eldebrink 0 Lopez 0 FENER Williams 15/15r Zahui B 14/12r McBride 12/6r Iagupova 11 Cakir 2/6r Canitez 0 Stokes 0
October 21, 2021
Sopron vs. Schio 67-58 SOP Hatar 25/12r Williams 17 Jovanovic 11 SCH Laksa 17 Gruda 12/8r Mestdagh 8 Collier 4