Spain copied other leagues, moving opening weekend to one venue as all games were played in Madrid. Al-Qazeres started play with an 83-55 win over Promete thanks to Joy Brown. Shayla Cooper made her professional debut in the win while Precious Hall did the same in the loss. Girona bounced back quickly from the Super Cup loss with a 71-53 win over Bembibre. In the loss, Quinn Dornstauder and Brittany Brown made their professional debuts and Elin Gustavsson returned to Europe after her college career. Avenida welcomed Estudiantes to the top division by beating them 82-58. The other newly promoted team did better as Belen Arrojo fired Sant Adria past Aisha Sutherland and Gernika 80-73. The rest of the games were played on Sunday, starting with Araski beating Alisia Jenkins and Zamarat 63-54. The losing side featured multiple players returning to Europe from college careers in Marina Lizarazu, Celia Garcia Paunero, and Ivana Kmetovska. Gipuzkoa beat Sedis 72-68 as Ellen Nystrom returned to Europe. In the loss, Mehryn Kraker and Caitlyn Ramirez started their professional careers and Ariadna Pujol returned to her home country after her college career. The weekend concluded with Jamie Weisner and Ferrol beating Shacobia Barbee and Zaragoza 90-81 as Alexis Prince also made her overseas debut.
September 30, 2017
Promete vs. Al-Qazeres 55-83 PRO L. Knight 11/6r Hall 10 W. Knight 10 Da Silva 3/8r ALQ Brown 26/7r Cooper 12/7r Montenegro 11/10r Foraste 11 Nascimento 10/7r
Girona vs. Bembibre 71-53 GIR Alminaite 13/9r Traore 13 Mendy 12 Conde 9/6r Evans 6/6r Martinez 5/7a Gomes Colhado 4 Romeo 2 BEM Dornstauder 15 Brown 12/8r Gustavsson 3
Avenida vs. Estudiantes 82-58 AVE Robinson 19/9r Dominguez 15 Asurmendi 13 Elonu 12 Moss 8 Abdi 7 Quevedo 6 De Souza 0 EST Baker 13 Menendez 11 Quirante 10
Gernika vs. Sant Adria 73-80 GER Sutherland 22/15r Gomez 15/9a Molina-Prados 12 Alston 9 SAN Arrojo 25/6r Riley 15 Vila 5
October 1, 2017
Araski vs. Zamarat 63-54 ARA Van Den Adel 17 Agirre 12 Etxarri 10/6r Silva 9/6r Forster 4/7r ZAM Jenkins 24/9r Lopez 12 Lizarazu 8/9r Butler 5 Garcia Paunero 2 Kmetovska 0
Gipuzkoa vs. Sedis 72-68 GIP Weaver 19/8r Brkic 13 Gonzalez 13 Nystrom 11/8r Sarr 10 SED Kraker 14 Rosset 13 Vilaro 11 Richards 8 Ramirez 6 Pujol 0
Ferrol vs. Zaragoza 90-81 FER Weisner 21 Prince 15 Perez 14/16r/7a Vanderwal 14 ZAR Barbee 23/6r Ferrari 18/7a Abalde 13 Zlatanova 12/11r Ocete 11/10a